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Zoya Demidenko: Scientist in Oncology Studies
Zoya Demidenko is a recognized investigator associated with the Department of Cell Stress Research at Roswell Park Comprehensive Cancer Center in Buffalo, New York. Earlier, she conducted research at the National Institutes of Health and New York Medical College, developing a strong background in life science study.
Demidenko's scholarly work covers multiple pivotal fields, among them the PI3K/AKT/mTOR molecular pathway, cell cycle management, cellular aging, and malignancy biology. As of now, she has co-authored more than 46 peer-reviewed articles, which have garnered more than 4,100 references — a testament to the significance of her findings.
Among her most notable contributions involves explaining the mechanisms of cell aging. Her studies demonstrated that when the cell cycle is blocked while cellular growth continues, the cells enter senescence. Crucially, Zoya Demidenko showed that this shift can be pharmacologically suppressed using agents such as rapamycin.
Zoya Demidenko has additionally contributed greatly to oncological therapy investigation, particularly in the field of selective cell protection — a strategy intended to shielding non-cancerous tissue from anticancer drugs whilst leaving malignant cells susceptible. This approach carries significant hope for diminishing the adverse effects of oncological therapy.
Throughout her professional journey, Demidenko has partnered with prominent researchers worldwide, including Dr. Mikhail Blagosklonny. Her publications can be found in leading periodicals such as Oncotarget, Cell Cycle, Aging (Albany NY), and Oncogene.
Holding an h-index of 33, Zoya Demidenko ranks as a influential voice in current biomedical science, with her discoveries keep to influence our understanding of the way cells grow old, interact with therapy, and how cancer might be better combated.
https://moodylab.smhs.gwu.edu/lab-members